This article emphasizes the importance of person-centered care (PCC) in healthcare delivery, particularly for adolescents and young people living with HIV. It highlights the need to shift power dynamics and promote client involvement, trust, and autonomy. Practical strategies for implementing PCC in African countries are discussed, including staff capacity-building, sensitization, peer support, community-led monitoring, and quality improvement plans. The article underscores the crucial role of youth in shaping and improving healthcare services, and the significance of an enabling work environment to support PCC. Download the article to explore practical recommendations and insights on promoting client-centered care and strengthening health systems.